Hypersensitivity to Alpros cream is a contraindication. In addition, Alpros Cream should not be used in following cases:

• If you have underlying disorders such as drop in blood pressure when going from a lying/sitting to a standing position, history of a heart attack, and syncope (dizziness).
• If you have an abnormally formed penis.
• If you have an inflammation or infection of the penis.
• If you have been told not to have sex for health reasons such as heart problems or a recent stroke.
• If your partner is pregnant, breast feeding or of childbearing potential unless you use a condom barrier.

Alpros cream is supplied in PE ampule, a single dose of cream:

• Wash your hands before applying Alpros.
• Remove the PE ampule from the sachet by tearing fully down the seal from the middle of the top edge. Save the sachet for discarding the used ampule later.
• Bring the contents of the single-dose ampule to room temperature by rolling the ampule between your hands (or keep it in your hands for a few minutes).
• Twist the head of ampule to open it.
• Use the ampule directly to apply Alpros at the meatus or opening of the penis. The onset of
  effect is within 5 to 30 minutes after application. The duration of effect is approximately one to two hours.

Note: urinating directly after application will significantly reduce the effect, so try to go to the bathroom before applying the cream.